Synergistic Effects of Intermittent Fasting and Vitamin C on Liver Histology, Body Weight, and Fasting Blood Glucose in Glucose-Loaded Male Wistar Rats
Student: Ahmed Opeyemi Saheed (Project, 2025)
Department of Human Physiology
University of Ilorin, Kwara State
Abstract
The study evaluated the combined effects of intermittent fasting (IF) and Vitamin C on liver histology, body weight, and fasting blood glucose (FBG) in glucose-loaded male Wistar rats. While initial FBG levels were similar across groups, significant differences emerged by Week 3 and Week 5. Histological analysis revealed severe liver damage in the glucose-only group, moderate improvement with IF alone, and near-normal liver structure in the IF + Vitamin C group. These findings suggest a strong synergistic effect in reversing glucose-induced liver injury and restoring metabolic balance.
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For the full publication, please contact the author directly at: saheedahmedopeyemi5501@gmail.com
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- Ekiti State University 58
- Ekiti State University, Ado-Ekiti, Ekiti State 881
- Elizade University, Ilara-Mokin, Ondo State 100
- Emmanuel Alayande College of Education, Oyo. (affl To Ekiti State Univ) 2
- Enugu State Polytechnic, Iwollo, Enugu State 4
- Enugu State University of Science and Technology, Enugu, Enugu State 29
- Evangel University, Akaeze, Ebonyi State 2
- FCT COLLEGE OF EDUCATION, ZUBA ,( AFFILIATED TO ABU, ZARIA), FCT-ABUJA 5
- Federal College of Agricultural Produce Tech, Hotoro Gra Ext, Kano, Kano State 2
- Federal College of Educ. (Special), Oyo, Oyo State (Aff To Uni. Ibadan) 10