Synergistic Effects of Intermittent Fasting and Vitamin C on Liver Histology, Body Weight, and Fasting Blood Glucose in Glucose-Loaded Male Wistar Rats
Student: Ahmed Opeyemi Saheed (Project, 2025)
Department of Human Physiology
University of Ilorin, Kwara State
Abstract
The study evaluated the combined effects of intermittent fasting (IF) and Vitamin C on liver histology, body weight, and fasting blood glucose (FBG) in glucose-loaded male Wistar rats. While initial FBG levels were similar across groups, significant differences emerged by Week 3 and Week 5. Histological analysis revealed severe liver damage in the glucose-only group, moderate improvement with IF alone, and near-normal liver structure in the IF + Vitamin C group. These findings suggest a strong synergistic effect in reversing glucose-induced liver injury and restoring metabolic balance.
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For the full publication, please contact the author directly at: saheedahmedopeyemi5501@gmail.com
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Institutions
- Sokoto State University, Sokoto, Sokoto State 42
- St. Albert The Great Major Seminary, Abeokuta. (affl. To University of Benin) 1
- Sule Lamido University, Kafin Hausa, Jigawa State 4
- Tai Solarin University of Education, Ijagun, Ogun State 18
- Tansian University, Oba, Anambra State 1
- Taraba State University, Jalingo, Taraba State 32
- Temple-Gate Polytechnic, Osisioma, Abia State 1
- The Oke-Ogun Polytechnic, Saki, Oyo State 6
- The Polytechnic, Ibadan, Oyo State 13
- THOMAS ADEWUMI UNIVERSITY, OKO-IRESE, KWARA STATE 1